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How to Position Your Gateway for Failure:The Ten Don’ts of Gateway DesignAbstractScience gateways are accelerators for science and education, providing user-friendly access to powerful computational resources and data analysis tools. Sustained science gateways frameworks such as Hubzero, Tapis, and Galaxy demonstrate the potential for gateways to revolutionize scientific exploration.However, despite initial promise, many gateway projects struggle to transition from prototypes to sustainable, long-term services. Well-intentioned, yet ultimately unsuccessful, gateways are part of the scientific landscape. This raises a critical question: what factors contribute to the demise of science gateways, and how can we avoid these pitfalls to ensure the success of future endeavors?This paper delves into the ten most common pitfalls that lead to science gateway failure. By analyzing these roadblocks, we aim to equip new and developing gateway initiatives with suggestions for long-term success. Our research draws on the collective experiences of numerous gateway projects.We identified critical areas where focused attention and strategic planning are essential. This knowledge will enable the development of good practices that nurture vibrant gateway communities and ensure the long-term sustainability of these valuable research tools.